Ethanol → 2-(6-Methyl-1H-indol-3-yl)ethan-1-amine

HRID 725062노트

반응식

HRID 725062 반응식
[CH3:1][C:2]1[C:10](Br)=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C(O)C>C(N(CC)CC)C>[CH3:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 702EthanolHCID 15274383HCID 15274383, 화합물

생성물 1

HCID 1900062-(6-Methyl-1H-indol-3-yl)ethan-1-amine

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

A sample of 6-methyl-7-bromo-1H-indole-3-ethanamine was contacted with Pd/C H2 in the presence of ethanol and triethylamine. The resulting material was evaporated and partitioned between base/CHCl3. The organic phase was dried, concentrated, and dried. The resulting material was taken up into methanol and added to ethereal HCl. The resulting material was washed and vacuum dried.

후처리

  1. customThe resulting material was evaporated
  2. custompartitioned between base/CHCl3
  3. customThe organic phase was dried
  4. concentrationconcentrated
  5. customdried
  6. additionadded to ethereal HCl
  7. washThe resulting material was washed
  8. customvacuum dried

출처 및 근거

ORD 기록
ord-10ba96c956e94c0689d3d24e36f3db86
출처 데이터셋
uspto-grants-1998_01
특허 번호
US05705519

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