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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 72541생성일: 2026년 10월 25일

Tert-butyl 3-((3-fluorophenoxy)methyl)piperidine-1-carboxylate → Methyl 4-(1-(5-chloro-2-(3-((3-fluorophenoxy)methyl)piperidin-1-yl)nicotinamido)cyclopropyl)benzoate

https://huagongshe.com/reaction/72541

반응식

참여 물질

역할이름HCID투입량
반응물Tert-butyl 3-((3-fluorophenoxy)methyl)piperidine-1-carboxylateHCID 67958503—
반응물Methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoateHCID 86697873—
생성물Methyl 4-(1-(5-chloro-2-(3-((3-fluorophenoxy)methyl)piperidin-1-yl)nicotinamido)cyclopropyl)benzoateHCID 67958004112%

반응 단계

The title compound (D203) (97 mg) was prepared according to the experimental procedure described in Description 160 starting from tert-butyl 3-((3-fluorophenoxy)methyl)piperidine-1-carboxylate (D45) (100 mg, 0.323 mmol) and reacting in the second step with methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate (D97) (59 mg, 0.161 mmol).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08828987B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-fd19a8d074d14285b2fe826d89f7c259
출처 메모uspto-grants-2014_09