1-Naphthalenesulfonyl chloride → alpha-Naphthyl-p-methylphenyldisulfone

HRID 725718노트

반응식

HRID 725718 반응식
[OH2:1].[OH2:2].[C:3]1([CH3:12])[CH:8]=[CH:7][C:6]([S:9]([O-:11])=[O:10])=[CH:5][CH:4]=1.[Na+].[C:14]1(S(Cl)(=O)=O)[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1>O>[C:22]1([C:5]2[CH:4]=[C:3]([CH3:12])[CH:8]=[CH:7][C:6]=2[S:9](=[O:11])(=[O:10])[S:9]([C:6]2[CH:7]=[CH:8][C:3]([CH3:12])=[CH:4][C:5]=2[C:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH:17]=[CH:16][CH:15]=2)(=[O:2])=[O:1])[C:23]2[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:19]=[CH:20][CH:21]=1

참가 물질

4

반응물 2

HCID 665601-Naphthalenesulfonyl chlorideHCID 23678556Sodium toluene-4-sulphinate dihydrate

생성물 1

HCID 86751875alpha-Naphthyl-p-methylphenyldisulfone수율 46.3%

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

11.8 g of sodium p-toluenesulfinate dihydrate were dissolved in 20 ml of water, and 11.3 g of α-naphthalenesulfonic acid chloride were added thereto and reacted for 24 hours at room temperature while stirring. 250 ml of water were added thereto, the precipitate formed were taken out by filtration, and this was recrystallized from a mixed solvent comprising benzene and ethanol. Thus, 6.5 g of α-naphthyl-p-methylphenyldisulfone (PAG 5-6) were obtained.

후처리

  1. customreacted for 24 hours at room temperature
  2. customthe precipitate formed
  3. filtrationwere taken out by filtration
  4. customthis was recrystallized from a mixed solvent comprising benzene and ethanol

출처 및 근거

ORD 기록
ord-d8a76e65b386458598b62f89ec27914a
출처 데이터셋
uspto-grants-1998_01
특허 번호
US05707776

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