Hexane → 4,8-Dimethylnona-3,7-dien-2-ol

HRID 725772

반응식

HRID 725772 반응식
C[Mg]Cl.[CH3:4][C:5](=[CH:7][CH2:8][CH2:9]/[C:10](=[CH:12]/[CH:13]=[O:14])/[CH3:11])[CH3:6].[NH4+].[Cl-].[CH3:17]CCCCC>COC(C)(C)C.O>[CH3:11][C:10]([CH2:9][CH2:8][CH:7]=[C:5]([CH3:4])[CH3:6])=[CH:12][CH:13]([OH:14])[CH3:17]

참가 물질

7

반응물 4

HCID 8058HexaneHCID 25517Ammonium ChlorideHCID 638011CitralHCID 178418332HCID 178418332, 화합물

생성물 1

HCID 1068744,8-Dimethylnona-3,7-dien-2-ol

시약·촉매·용매 2

HCID 962Water용매HCID 15413tert-Butyl methyl ether용매2회

반응 조건

온도
10 °C

실험 절차

1 l of t-butyl methyl ether and 1.05 l of 3N methyl magnesium chloride solution were placed under N2 in a 41/2 l sulphonation flask having a thermometer, stirrer and dropping funnel and 456 g of geranial in 500 ml of t-butyl methyl ether were added dropwise at 0° C. The mixture was stirred at 10° C. for 1 hour and poured on to 3 kg of ice and 500 g of NH4Cl and treated with 1 l of hexane. After mixing well the H2O phase was separated and washed neutral 3 times with 500 ml of NH4Cl solution, dried and evaporated.

후처리

  1. customwas separated
  2. washwashed neutral 3 times with 500 ml of NH4Cl solution
  3. customdried
  4. customevaporated

출처 및 근거

ORD 기록
ord-f339ef21ee2f4548b11a6ee422594f82
출처 데이터셋
uspto-grants-1998_01
특허 번호
US05707961

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