Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aniline → (2S,4R)-2-Anilinomethyl-N-t-butoxycarbonyl-4-t-butyldimethylsiloxypyrrolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | tert-Butyl (2S,4R)-4-((tert-butyldimethylsilyl)oxy)-2-formylpyrrolidine-1-carboxylate | HCID 10969557 | — |
| 생성물 | (2S,4R)-2-Anilinomethyl-N-t-butoxycarbonyl-4-t-butyldimethylsiloxypyrrolidine | HCID 57283160 | 82% |
반응 단계
(2S,4R)-2-Anilinomethyl-N-t-butoxycarbonyl-4-t-butyldimethylsiloxypyrrolidine (995 mg, yield: 82%) was prepared as a yellow oily substance, from (2S,4R)-N-t-butoxycarbonyl-4-t-butyldimethylsiloxyprolinal (990 mg, 3 mmol) and aniline (0.3 ml, 3.3 mmol), in the same manner as in Reference Example 95-2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05707987 |
| 출처 데이터셋 | uspto-grants-1998_01 |
| ORD ID | ord-9770d381dfb140d5ae8ddf9de57590f9 |
| 출처 메모 | uspto-grants-1998_01 |