5-(Methylsulfanyl)thiophene-2-carbaldehyde → (E)-3-(2-methylmercaptothien-5-yl)-2-[(3-phenyl-n-propyl)aminosulfonyl]acrylonitrile

HRID 726734노트

반응식

HRID 726734 반응식
[CH3:1][S:2][C:3]1[S:4][C:5]([CH:8]=O)=[CH:6][CH:7]=1.[C:10]1([CH2:16][CH2:17][CH2:18][NH:19][S:20]([CH2:23][C:24]#[N:25])(=[O:22])=[O:21])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH3:1][S:2][C:3]1[S:4][C:5](/[CH:8]=[C:23](/[S:20]([NH:19][CH2:18][CH2:17][CH2:16][C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)(=[O:22])=[O:21])\[C:24]#[N:25])=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 27369975-(Methylsulfanyl)thiophene-2-carbaldehydeHCID 15410494(3-Phenyl-n-propyl)aminosulfonylacetonitrile

생성물 1

HCID 15410667(E)-3-(2-methylmercaptothien-5-yl)-2-[(3-phenyl-n-propyl)aminosulfonyl]acrylonitrile

실험 절차

Reaction of 2-methylmercaptothiophen-5-carboxaldehyde and (3-phenyl-n-propyl)aminosulfonylacetonitrile as in Example 1 gave (E)-3-(2-methylmercaptothien-5-yl)-2-[(3-phenyl-n-propyl)aminosulfonyl]acrylonitrile

출처 및 근거

ORD 기록
ord-215fd1ce8fd14cf184b925abca130a97
출처 데이터셋
uspto-grants-1998_01
특허 번호
US05710173

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