Sulfuric Acid → Xanthone-2-carboxylic acid

HRID 726769노트

반응식

HRID 726769 반응식
[C:1]([C:4]1[CH:19]=[CH:18][C:7]([O:8][C:9]2[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=2[C:11]([OH:13])=O)=[CH:6][CH:5]=1)([OH:3])=[O:2].S(=O)(=O)(O)O>O>[O:13]=[C:11]1[C:6]2[CH:5]=[C:4]([C:1]([OH:3])=[O:2])[CH:19]=[CH:18][C:7]=2[O:8][C:9]2[C:10]1=[CH:14][CH:15]=[CH:16][CH:17]=2

참가 물질

4

반응물 2

HCID 1118Sulfuric AcidHCID 226650732-(4-Carboxyphenoxy)benzoic acid

생성물 1

HCID 473472Xanthone-2-carboxylic acid수율 87.6%

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
80 °C

실험 절차

A mixture of 29.9 g (0.11 mol) of 2-(4-carboxyphenoxy)benzoic acid (Example 10e) and 250 ml of concentrated sulfuric acid is heated at 80° C. for one hour. The resulting solution is then poured onto about 2.5 litres of water and the mixture is stirred vigorously for 30 minutes. The product which has precipitated is filtered off, washed with water and dried under a high vacuum. 23.15 g (85%) of 9-oxo-9H-xanthene-2-carboxylic acid, melting point >280° C., result as a beige powder.

후처리

  1. customThe product which has precipitated
  2. filtrationis filtered off
  3. washwashed with water
  4. customdried under a high vacuum

출처 및 근거

ORD 기록
ord-6d243c70383e49c49ce727479afd48a6
출처 데이터셋
uspto-grants-1998_01
특허 번호
US05710198

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