HCID 19707490, 화합물 → Methyl 3-(3-aminophenoxy)benzoate
반응식
[C:1]([C:5]1[CH:6]=[C:7]([O:11][C:12]2[CH:13]=[C:14]([N+:18]([O-])=O)[CH:15]=[CH:16][CH:17]=2)[CH:8]=[CH:9][CH:10]=1)([O:3][CH3:4])=[O:2]>CO.[Pd]>[C:1]([C:5]1[CH:6]=[C:7]([O:11][C:12]2[CH:13]=[C:14]([NH2:18])[CH:15]=[CH:16][CH:17]=2)[CH:8]=[CH:9][CH:10]=1)([O:3][CH3:4])=[O:2]참가 물질
4
실험 절차
To a solution of 1 (440 mg) in 30 mL of methanol under a nitrogen atmosphere was added 10% Pd/C (30 mg). The solution was purged with H2 gas, then stirred at room temperature under a balloon atmosphere of H2. After 8 h, the reaction was flushed with nitrogen and filtered through celite to remove the catalyst, then concentrated in vacuo. The resulting brown oil was used without further purification.
후처리
- customThe solution was purged with H2 gas
- customthe reaction was flushed with nitrogen
- filtrationfiltered through celite
- customto remove the catalyst
- concentrationconcentrated in vacuo
- customThe resulting brown oil was used without further purification
출처 및 근거
- ORD 기록
- ord-25f92af004524f0abfbf98156f624366
- 출처 데이터셋
- uspto-grants-1998_01
- 특허 번호
- US05710171
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