L-Gulose → Anhydro-d-mannosan

HRID 728206노트

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HRID 728206 반응식
O=[CH:2][C@H:3]([C@H:5]([C@@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4]>O>[C@@H:11]12[O:12][CH2:2][C@H:3]([O:4]1)[C@@H:5]([OH:6])[C@H:7]([OH:8])[C@@H:9]2[OH:10]

참가 물질

3

반응물 1

HCID 80127L-Gulose

생성물 1

HCID 11947765Anhydro-d-mannosan

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Syrupy L-gulose was heated on a steam bath in water with strong acid resin (Dowex 50 W-X8, H+ form) for 64 h. The solution was then filtered, the resin washed with water, and the combined filtrate was passed onto a column packed with strong base resin (Amberlite IRA-900, OH- form). The column was washed with distilled water to elute the title compound which crystallized from ethanol. Recrystallized from ethanol it has mp 155.5°-156.5° C. The column was then immediately washed with aqueous acetic acid (M) to elute unreacted L-gulose which was recycled to provide further title compound.

후처리

  1. filtrationThe solution was then filtered
  2. washthe resin washed with water
  3. washThe column was washed with distilled water
  4. washto elute the title compound which
  5. customcrystallized from ethanol
  6. customRecrystallized from ethanol it
  7. washThe column was then immediately washed with aqueous acetic acid (M)
  8. washto elute unreacted L-gulose which

출처 및 근거

ORD 기록
ord-7071e9fa7c1e442a8c0394816aa747f6
출처 데이터셋
uspto-grants-1991_09
특허 번호
US05047518

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