1-Pyrrolidineethanol → 1-[2-[4-(1H-Imidazol-1-yl)-1,2,5-thiadiazol-3-yloxy]ethyl]pyrrolidine

반응식

Cl[C:2]1[C:6]([N:7]2[CH:11]=[CH:10][N:9]=[CH:8]2)=[N:5][S:4][N:3]=1.[OH:12][CH2:13][CH2:14][N:15]1[CH2:19][CH2:18][CH2:17][CH2:16]1>>[N:7]1([C:6]2[C:2]([O:12][CH2:13][CH2:14][N:15]3[CH2:19][CH2:18][CH2:17][CH2:16]3)=[N:3][S:4][N:5]=2)[CH:11]=[CH:10][N:9]=[CH:8]1

참가 물질

반응물 2

HCID 762881-Pyrrolidineethanol

HCID 156624193-chloro-4-(1H-imidazol-1-yl)-1,2,5-thiadiazole

생성물 1

HCID 545665231-[2-[4-(1H-Imidazol-1-yl)-1,2,5-thiadiazol-3-yloxy]ethyl]pyrrolidine

실험 절차

Following the procedures of Example 1, the title compound is prepared from 3-chloro-4-(1H-imidazol-1-yl)-1,2,5-thiadiazole and 1-(2-hydroxyethyl)pyrrolidine.

출처 및 근거

ORD 기록: ord-55b022515294417ba0726a9d420ffe6c
출처 데이터셋: uspto-grants-1991_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05051420

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