4-Benzyl-2-cyano-1-phenylpiperazine → 1-Phenyl-4-(phenylmethyl)-2-piperazinemethanamine

HRID 728912노트

반응식

HRID 728912 반응식
[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH2:9][CH:8]2[C:20]#[N:21])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH2:9][CH:8]2[CH2:20][NH2:21])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 149987524-Benzyl-2-cyano-1-phenylpiperazineHCID 21226445Aluminium lithium hydride

생성물 1

HCID 149987701-Phenyl-4-(phenylmethyl)-2-piperazinemethanamine

실험 절차

In a manner similar to Preparation 2, react 1-phenyl-4-(phenylmethyl)-2-piperazinecarbonitrile (16.6 g, 60 mmol) with lithium aluminum hydride (6.8 g, 180 mmol) to obtain the title compound.

후처리

  1. customIn a manner similar to Preparation 2

출처 및 근거

ORD 기록
ord-347d02fb057a4f46b75e25381f1c3c18
출처 데이터셋
uspto-grants-1991_09
특허 번호
US05051422

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