Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorosulfonic acid → 4-(1H-Imidazol-1-yl)benzenesulfonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorosulfonic acid | HCID 24638 | — |
| 반응물 | 1-Phenylimidazole | HCID 81595 | — |
| 생성물 | 4-(1H-Imidazol-1-yl)benzenesulfonyl chloride | HCID 14998830 | — |
반응 단계
To chlorosulfonic acid cooled to 0° C. in an ice bath is added portionwise 1-phenyl-1H-imidazole. Monitor the progress of the reaction bythin-layer chromatography. When the reaction is complete, quench the mixture on ice. Saturated aqueous NaHCO3 is added until the solution is no longer acidic. Extract the mixture with CH2Cl2. Dry the organic layer over anhydrous Na2SO4 and remove the solvent in vacuo to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05051422 |
| 출처 데이터셋 | uspto-grants-1991_09 |
| ORD ID | ord-6cc879f52e8e41ef9074507710849770 |
| 출처 메모 | uspto-grants-1991_09 |