4-Methanesulfonamidobenzene-1-sulfonyl chloride → N-[[4-(2,6-Dichlorophenyl)-1-[(3,4-dimethoxyphenyl)methyl]piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]-N-(2-propenyl)benzenesulfonamide
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([O:24][CH3:25])[CH:17]=2)[CH:11]([CH2:26][NH:27][CH2:28][CH:29]=[CH2:30])[CH2:10]1.[CH3:31][S:32]([NH:35][C:36]1[CH:41]=[CH:40][C:39]([S:42](Cl)(=[O:44])=[O:43])=[CH:38][CH:37]=1)(=[O:34])=[O:33]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([O:24][CH3:25])[CH:17]=2)[CH:11]([CH2:26][N:27]([CH2:28][CH:29]=[CH2:30])[S:42]([C:39]2[CH:38]=[CH:37][C:36]([NH:35][S:32]([CH3:31])(=[O:34])=[O:33])=[CH:41][CH:40]=2)(=[O:44])=[O:43])[CH2:10]1참가 물질
3
반응물 2
생성물 1
실험 절차
In a manner similar to Preparation 3, react 4-(2,6-dichlorophenyl)-1-[(3,4-dimethoxyphenyl)methyl]-N-(2-propenyl)-2-piperazinemethanamine with 4-[(methylsulfonyl)amino]benzenesulfonyl chloride to obtain the title compound.