HCID 14998780, 화합물 → 4-(3-Chlorophenyl)-1-[(3,4-dimethoxyphenyl)methyl]-N-(1-methylethyl)-2-piperazinemethanamine
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([O:23][CH3:24])[CH:16]=3)[CH:10]([C:25]([NH:27][CH:28]([CH3:30])[CH3:29])=O)[CH2:9]2)[CH:5]=[CH:6][CH:7]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([O:23][CH3:24])[CH:16]=3)[CH:10]([CH2:25][NH:27][CH:28]([CH3:30])[CH3:29])[CH2:9]2)[CH:5]=[CH:6][CH:7]=1참가 물질
3
실험 절차
In a manner similar to Preparation 2, react 4-(3-chlorophenyl)-1-[(3,4-dimethoxyphenyl)methyl]-N-(1-methylethyl)-2-piperazinecarboxamide with lithium aluminum hydride to obtain the title compound.
후처리
- customIn a manner similar to Preparation 2
출처 및 근거
- ORD 기록
- ord-648a8c80e74c49909e3d3029e0fd4f5d
- 출처 데이터셋
- uspto-grants-1991_09