Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
8,9-Difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid → Ofloxacin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 8,9-Difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid | HCID 534278 | — |
| 반응물 | 4-(t-Butyldimethylsilyl)-1-methyl piperazine | HCID 19434781 | — |
| 생성물 | Ofloxacin | HCID 4583 | — |
반응 단계
In a manner similar to that of Example 4, 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido [1,2,3-de]-1,4-benzoxazin- 6-carboxylic acid (II, X: fluoro) is reacted with 4-(t-butyldimethylsilyl)-1-methylpiperazine (III, R2, R3 and R4 : methyl; R5 : t-butyl) to obtain a solid compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05051505 |
| 출처 데이터셋 | uspto-grants-1991_09 |
| ORD ID | ord-13e9f7b309c54757b66a5042d743ec3c |
| 출처 메모 | uspto-grants-1991_09 |