4-Cyclohexylbenzenamine → HCID 11619078, 화합물
반응식
Cl[C:2]1[C:3](=[O:19])[N:4]([CH2:15][CH2:16][O:17][CH3:18])[S:5](=[O:14])(=[O:13])[C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[CH:20]1([C:26]2[CH:32]=[CH:31][C:29]([NH2:30])=[CH:28][CH:27]=2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH:20]1([C:26]2[CH:27]=[CH:28][C:29]([NH:30][C:2]3[C:3](=[O:19])[N:4]([CH2:15][CH2:16][O:17][CH3:18])[S:5](=[O:14])(=[O:13])[C:6]=3[C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)=[CH:31][CH:32]=2)[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]1참가 물질
3
실험 절차
The title compound was prepared from 4-chloro-2-(2-methoxyethyl)-5-phenylisothiazol-3(2H)-one 1,1-dioxide and 4-cyclohexylaniline in a similar manner as described for e.g. Examples 9 and 13. 1H NMR (400 MHz, CD3CN): δ 1.19-1.44 (m, 5H), 1.64-1.84 (m, 5H), 2.31-2.40 (m, 1H), 3.38 (s, 3H), 3.72 (t, 2H), 3.90 (t, 2H), 6.67-6.72 (m, 2H), 6.80-6.85 (m, 2H), 7.05-7.14 (m, 4H), 7.19-7.24 (m, 1H), 7.75 (bs, 1H); Mass Spectrum: M+H+ 441.
출처 및 근거
- ORD 기록
- ord-809ad94fd6ad4958bfbbb2ee21ed76a0
- 출처 데이터셋
- uspto-grants-2009_09