Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → Ammonia
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | Sulfolane | HCID 31347 | — |
| 반응물 | Benzenesulfonic acid, 2-amino-5-nitro- | HCID 66786 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Ammonia | HCID 222 | — |
| 생성물 | 2-Amino-5-nitrobenzenesulfonamide | HCID 15358386 | — |
반응 단계
The commercially available sodium salt of 2-amino-5-nitro-benzenesulfonic acid can be converted to the corresponding sulfonyl chloride with phosphoryl chloride in the presence of a suitable co-solvent, such as sulfolane. Treatment with ammonia, e.g., ammonia solution in methanol or ammonia gas, affords the desired 2-amino-5-nitro-benzenesulfonamide intermediate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07582754B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-0531f833112e468eaba84e598a136d32 |
| 출처 메모 | uspto-grants-2009_09 |