Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodine chloride → 2-Methoxy-5-Methylaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodine chloride | HCID 24640 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 7-Iodo-N-(2-methoxy-5-methylphenyl)-1-benzofuran-5-sulfonamide | HCID 66892506 | — |
| 생성물 | 2-Methoxy-5-Methylaniline | HCID 8445 | — |
반응 단계
7-iodo-N-(2-methoxy-5-methylphenyl)-1-benzofuran-5-sulfonamide is produced starting from 2,3-dihydrobensofuran. Treatment with chlorosulfonic acid gives the corresponding sulfonyl chloride, which is iodinated using iodine monochloride. Aromatization is done using NBS, resulting in 7-iodo-N-(2-methoxy-5-methylphenyl)-1-benzofuran-5-sulfonamide after treatment with cresidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07582767B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-976addb137994549b4eb022567162e52 |
| 출처 메모 | uspto-grants-2009_09 |