2,3-Dichloro-5-(trifluoromethyl)pyridine → Methyl 4-(N-(benzofuran-6-ylmethyl)-N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)sulfamoyl)benzoate
반응식
Cl[C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=1.[O:13]1[C:17]2[CH:18]=[C:19]([CH2:22][NH:23][S:24]([C:27]3[CH:36]=[CH:35][C:30]([C:31]([O:33][CH3:34])=[O:32])=[CH:29][CH:28]=3)(=[O:26])=[O:25])[CH:20]=[CH:21][C:16]=2[CH:15]=[CH:14]1>>[O:13]1[C:17]2[CH:18]=[C:19]([CH2:22][N:23]([C:2]3[C:7]([Cl:8])=[CH:6][C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=3)[S:24]([C:27]3[CH:36]=[CH:35][C:30]([C:31]([O:33][CH3:34])=[O:32])=[CH:29][CH:28]=3)(=[O:26])=[O:25])[CH:20]=[CH:21][C:16]=2[CH:15]=[CH:14]1참가 물질
3
실험 절차
The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3-dichloro-5-(trifluoromethyl)pyridine and methyl 4-(N-(benzofuran-6-ylmethyl)sulfamoyl)benzoate (step-1 of Example 2).
출처 및 근거
- ORD 기록
- ord-4d78afb93a4a4109aa72445bf541092a
- 출처 데이터셋
- uspto-grants-2014_09