2,3-Dichloro-5-(trifluoromethyl)pyridine → Methyl 4-(N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((1-methyl-1H-indazol-5-yl)methyl) sulfamoyl)-3-ethylbenzoate
반응식
Cl[C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=1.[CH2:13]([C:15]1[CH:16]=[C:17]([CH:22]=[CH:23][C:24]=1[S:25](=[O:39])(=[O:38])[NH:26][CH2:27][C:28]1[CH:29]=[C:30]2[C:34](=[CH:35][CH:36]=1)[N:33]([CH3:37])[N:32]=[CH:31]2)[C:18]([O:20][CH3:21])=[O:19])[CH3:14]>>[Cl:8][C:7]1[C:2]([N:26]([CH2:27][C:28]2[CH:29]=[C:30]3[C:34](=[CH:35][CH:36]=2)[N:33]([CH3:37])[N:32]=[CH:31]3)[S:25]([C:24]2[CH:23]=[CH:22][C:17]([C:18]([O:20][CH3:21])=[O:19])=[CH:16][C:15]=2[CH2:13][CH3:14])(=[O:39])=[O:38])=[N:3][CH:4]=[C:5]([C:9]([F:12])([F:11])[F:10])[CH:6]=1참가 물질
3
실험 절차
The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3-dichloro-5-(trifluoromethyl)pyridine and methyl 3-ethyl-4-(N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)benzoate (step-2 of Example 4).
출처 및 근거
- ORD 기록
- ord-71286f63b4d14286a5fa7c7a20afa743
- 출처 데이터셋