3,5-Dichloro-2-fluoropyridine → Methyl 4-(N-(3,5-dichloropyridin-2-yl)-N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoate
반응식
[Cl:1][C:2]1[C:3](F)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[CH3:10][N:11]1[C:19]2[C:14](=[CH:15][C:16]([CH2:20][NH:21][S:22]([C:25]3[CH:34]=[CH:33][C:28]([C:29]([O:31][CH3:32])=[O:30])=[CH:27][CH:26]=3)(=[O:24])=[O:23])=[CH:17][CH:18]=2)[CH:13]=[CH:12]1>>[Cl:1][C:2]1[C:3]([N:21]([CH2:20][C:16]2[CH:15]=[C:14]3[C:19](=[CH:18][CH:17]=2)[N:11]([CH3:10])[CH:12]=[CH:13]3)[S:22]([C:25]2[CH:26]=[CH:27][C:28]([C:29]([O:31][CH3:32])=[O:30])=[CH:33][CH:34]=2)(=[O:23])=[O:24])=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1참가 물질
3
실험 절차
The titled compound was prepared according to the procedure described in step-2 of Example 1 from 3,5-dichloro-2-fluoropyridine and methyl 4-(N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoate (step-1 of Example 6).
출처 및 근거
- ORD 기록
- ord-87e3ebb037274c31b0f93ed13560cb75
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08829026B2
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