3,5-Dichloro-2-fluoropyridine → HCID 66837916, 화합물

HRID 73071노트

반응식

HRID 73071 반응식
[Cl:1][C:2]1[C:3](F)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:19]=[CH:20][C:21]=1[S:22](=[O:36])(=[O:35])[NH:23][CH2:24][C:25]1[CH:26]=[C:27]2[C:31](=[CH:32][CH:33]=1)[N:30]([CH3:34])[CH:29]=[CH:28]2)[C:14]([O:16][CH2:17][CH3:18])=[O:15]>>[Cl:10][C:11]1[CH:12]=[C:13]([CH:19]=[CH:20][C:21]=1[S:22](=[O:36])(=[O:35])[N:23]([C:3]1[C:2]([Cl:1])=[CH:7][C:6]([Cl:8])=[CH:5][N:4]=1)[CH2:24][C:25]1[CH:26]=[C:27]2[C:31](=[CH:32][CH:33]=1)[N:30]([CH3:34])[CH:29]=[CH:28]2)[C:14]([O:16][CH2:17][CH3:18])=[O:15]

참가 물질

3

반응물 2

HCID 27832563,5-Dichloro-2-fluoropyridineHCID 66837930HCID 66837930, 화합물

생성물 1

HCID 66837916HCID 66837916, 화합물

실험 절차

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 3,5-dichloro-2-fluoropyridine and ethyl 3-chloro-4-(N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoate (step-1 of Example 8).

출처 및 근거

ORD 기록
ord-135a35cdfaff4cfda5129b53a6dceca7
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08829026B2

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