Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5-Dichlorobenzimidazole → 6-Chloro-2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-1H-benzoimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5-Dichlorobenzimidazole | HCID 335473 | — |
| 반응물 | 1-(3,5-Dichloropyridin-4-yl)piperazine | HCID 2799984 | — |
| 생성물 | 6-Chloro-2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-1H-benzoimidazole | HCID 57835081 | — |
반응 단계
The 2,5-dichloro-1H-benzoimidazole (0.37 g, 1.98 mmol, Example 20b) and 1-(3,5-dichloropyridin-4-yl)piperazine (0.46 g, 1.98 mmol, Maybridge) reacted under the conditions of Example 3c to give the title compound as a white solid. M.p. 258-260° C. MS (ESI, pos. ion) m/z: 382 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07582761B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-10a12fecc7624c79a96816a7018da4ac |
| 출처 메모 | uspto-grants-2009_09 |