1-(3,5-Dichloropyridin-4-yl)piperazine → HCID 178422317, 화합물

HRID 730732

반응식

HRID 730732 반응식
Cl[C:2]1[NH:6][C:5]2[CH:7]=[C:8]([CH3:12])[C:9]([Cl:11])=[CH:10][C:4]=2[N:3]=1.[Cl:13][C:14]1[CH:15]=[N:16][CH:17]=[C:18]([Cl:26])[C:19]=1[N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[Cl:11][C:9]1[C:8]([CH3:12])=[CH:7][C:5]2[N:6]=[C:2]([N:23]3[CH2:24][CH2:25][N:20]([C:19]4[C:18]([Cl:26])=[CH:17][N:16]=[CH:15][C:14]=4[Cl:13])[CH2:21][CH2:22]3)[NH:3][C:4]=2[CH:10]=1

참가 물질

3

반응물 2

HCID 27999841-(3,5-Dichloropyridin-4-yl)piperazineHCID 670339402,6-dichloro-5-methyl-1H-1,3-benzodiazole

생성물 1

HCID 178422317HCID 178422317, 화합물

실험 절차

The benzoimidazole from step (b) above (0.201 g, 1 mmol) and 1-(3,5-dichloropyridin-4-yl)piperazine (0.462 g, 2 mmol, Maybridge) reacted under the conditions of Example 1d to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 396 (M+1).

출처 및 근거

ORD 기록
ord-6fcb6e2b3d5b47918810bc6a709dc26f
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07582761B2

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