4-Bromo-2-methylbenzenesulfonyl chloride → 4-Bromo-2-methyl-N-((1-methyl-1H-indazol-5-yl)methyl)benzenesulfonamide

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[C:4]([CH3:12])[CH:3]=1.[CH3:13][N:14]1[C:22]2[C:17](=[CH:18][C:19]([CH2:23][NH2:24])=[CH:20][CH:21]=2)[CH:16]=[N:15]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:24][CH2:23][C:19]2[CH:18]=[C:17]3[C:22](=[CH:21][CH:20]=2)[N:14]([CH3:13])[N:15]=[CH:16]3)(=[O:10])=[O:9])=[C:4]([CH3:12])[CH:3]=1

참가 물질

반응물 2

HCID 27813384-Bromo-2-methylbenzenesulfonyl chloride

HCID 230001565-(Aminomethyl)-1-methyl-1H-indazole

생성물 1

HCID 668378964-Bromo-2-methyl-N-((1-methyl-1H-indazol-5-yl)methyl)benzenesulfonamide

실험 절차

The titled compound was prepared according to the procedure described in step-1 of Example 1 from 4-bromo-2-methylbenzene-1-sulfonyl chloride and (1-methyl-1H-indazol-5-yl)methanamine.

출처 및 근거

ORD 기록: ord-51bf8aacdc73483c86e76e3c45c98b44
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08829026B2

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