Pyridine, 2,3,5-trichloro- → Methyl 4-(N-(3,5-dichloropyridin-2-yl)-N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)-3-methylbenzoate

HRID 73105

반응식

HRID 73105 반응식
Cl[C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[CH:4][N:3]=1.[CH3:10][C:11]1[CH:12]=[C:13]([CH:18]=[CH:19][C:20]=1[S:21](=[O:35])(=[O:34])[NH:22][CH2:23][C:24]1[CH:25]=[C:26]2[C:30](=[CH:31][CH:32]=1)[N:29]([CH3:33])[N:28]=[CH:27]2)[C:14]([O:16][CH3:17])=[O:15]>>[Cl:8][C:7]1[C:2]([N:22]([CH2:23][C:24]2[CH:25]=[C:26]3[C:30](=[CH:31][CH:32]=2)[N:29]([CH3:33])[N:28]=[CH:27]3)[S:21]([C:20]2[CH:19]=[CH:18][C:13]([C:14]([O:16][CH3:17])=[O:15])=[CH:12][C:11]=2[CH3:10])(=[O:35])=[O:34])=[N:3][CH:4]=[C:5]([Cl:9])[CH:6]=1

참가 물질

3

반응물 2

HCID 27666Pyridine, 2,3,5-trichloro-HCID 66837895HCID 66837895, 화합물

생성물 1

HCID 66837848Methyl 4-(N-(3,5-dichloropyridin-2-yl)-N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)-3-methylbenzoate

실험 절차

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3,5-trichloropyridine and methyl 3-methyl-4-(N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)benzoate (step-2 of Example 26).

출처 및 근거

ORD 기록
ord-9d84b512a70244bd82eb965e7731e301
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08829026B2

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