Thionyl Chloride → 5-Bromo-1-chloro-2,3-dihydro-1H-indene

HRID 731181노트

반응식

HRID 731181 반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7](O)[CH2:6][CH2:5]2.S(Cl)([Cl:14])=O>C(Cl)Cl>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([Cl:14])[CH2:6][CH2:5]2

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 134862995-bromo-2,3-dihydro-1H-inden-1-ol

생성물 1

HCID 223495155-Bromo-1-chloro-2,3-dihydro-1H-indene

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A mixture of 47.2 (11.1 mmol) and thionyl chloride (44 mmol) in DCM (20 mL) was stirred at room temperature overnight. After evaporation of solvent, 47.3 was obtained and it was used without further purification.

후처리

  1. customAfter evaporation of solvent
  2. custom47.3 was obtained
  3. customit was used without further purification

출처 및 근거

ORD 기록
ord-5026e2f771874f2087328fd253aa1a6f
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07582803B2

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