Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-3-Hydroxypyridine → 2-(5-Methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridin-8-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-3-Hydroxypyridine | HCID 28114 | — |
| 반응물 | 4-(Bromoacetyl)-5-methyl-3-phenylisoxazole | HCID 2735531 | — |
| 생성물 | 2-(5-Methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridin-8-ol | HCID 24738184 | 4% |
반응 단계
As described for Example 2, 4-(bromoacetyl)-5-methyl-3-phenylisoxazole (commercially available) (140 mg, 0.5 mmol) was converted, using 2-amino-3-hydroxypyridine instead of 2-amino-3-methylpyridine, to the title compound (6 mg, 4%) which was obtained as a yellow foam. MS: m/e=292.1 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07585874B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-692fd11c6c804d22b114d0afcc345613 |
| 출처 메모 | uspto-grants-2009_09 |