Tetrahydro-4H-pyran-4-one → HCID 23112224, 화합물

HRID 731941노트

반응식

HRID 731941 반응식
[CH2:1]([NH:3][CH2:4][C:5]1[CH:10]=[C:9]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:8]=[CH:7][C:6]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH3:2].[O:22]1[CH2:27][CH2:26][C:25](=O)[CH2:24][CH2:23]1.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>C(O)(=O)C>[CH2:1]([N:3]([CH2:4][C:5]1[CH:10]=[C:9]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:8]=[CH:7][C:6]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH:25]1[CH2:26][CH2:27][O:22][CH2:23][CH2:24]1)[CH3:2]

참가 물질

5

반응물 3

HCID 121599Tetrahydro-4H-pyran-4-oneHCID 5049666Sodium triacetoxyborohydrideHCID 23112226HCID 23112226, 화합물

생성물 1

HCID 23112224HCID 23112224, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

Ethyl 2-[(ethylamino)methyl]biphenyl-4-carboxylate and tetrahydro-4H-pyran-4-one were treated with sodium triacetoxyborohydride in the presence of acetic acid to obtain ethyl 2-{[ethyl(tetrahydro-2H-pyran-4-yl)amino]methyl}biphenyl-4-carboxylate.

출처 및 근거

ORD 기록
ord-4cbb11fa13f7460c8d84b01a39cfb3e5
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07585878B2

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