Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzenepropanoic acid, 4-hydroxy-, methyl ester → Methyl 3-{4-[(4-{[(4-phenyl-1,3-thiazol-2-yl)(2-pyridin-2-ylethyl)amino]methyl}benzyl)oxy]phenyl}propanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzenepropanoic acid, 4-hydroxy-, methyl ester | HCID 79706 | — |
| 반응물 | (4-([(4-Phenyl-1,3-thiazol-2-yl)(2-pyridin-2-ylethyl)amino]methyl}phenyl)methanol | HCID 23143295 | — |
| 생성물 | Methyl 3-{4-[(4-{[(4-phenyl-1,3-thiazol-2-yl)(2-pyridin-2-ylethyl)amino]methyl}benzyl)oxy]phenyl}propanoate | HCID 23143288 | 57% |
반응 단계
The title compound was synthesized in the same manner as in Example 8 from (4-{[(4-phenyl-1,3-thiazol-2-yl)(2-pyridin-2-ylethyl)amino]methyl}phenyl)methanol and methyl 3-(4-hydroxyphenyl)propanoate by Mitsunobu reaction (yield 57%). Yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07585880B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-0eb6a71bc6ad415ea62f9cdb7fbd562b |
| 출처 메모 | uspto-grants-2009_09 |