Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-Chlorobutane-1-sulphonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1-Butanol, 4-chloro-, 1-acetate | HCID 23399 | — |
| 반응물 | Sodium Sulfite | HCID 24437 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Chlorobutane-1-sulphonyl chloride | HCID 74212 | — |
반응 단계
Add anhydrous sodium sulfite (16.8 g, 130 mmol) to a solution of 4-chlorobutyl acetate (20.0 g, 133 mmol) in water (50 mL) and reflux the mixture for 20 h. Cool to room temperature and add concentrated HCl (19.0 mL) and reflux for 1 h. Cool the mixture to room temperature, neutralize to about pH=7. Concentrate to about one half the volume, filter away the sodium chloride. Concentrate and dry to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07585885B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-d56b9ba0d8e84946ae969baed6e81415 |
| 출처 메모 | uspto-grants-2009_09 |