Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → trans-[2-(4-Bromophenyl)cyclopropyl]methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 3-Phenylprop-2-En-1-Ol | HCID 308 | — |
| 반응물 | (2E)-3-(4-bromophenyl)prop-2-en-1-ol | HCID 11183465 | — |
| 생성물 | trans-[2-(4-Bromophenyl)cyclopropyl]methanol | HCID 18651197 | — |
반응 단계
The title compound was prepared by the method of A. B. Charette and H. Lebel (Organic Synthesis, 1998, 76, 86-96) substituting trans-3-(4-Bromophenyl) prop-2-en-1-ol (the product from Example 1A) for 3-Phenyl-prop-2-en-1-ol. 1H NMR (300 MHz, CDCl3): δ 0.92-1.0 (m, 2H), 1.45-1.48 (m, 2H), 1.76-1.85 (m, 1H), 3.61 (d, J=7.5 Hz, 2H), 6.95 (d, J=9 Hz, 2H), 7.37 (d, J=9 Hz, 2H). MS (DCl—NH3) m/z 228 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829041B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-14bf0604c5af43b68f7aa39cd25dae3b |
| 출처 메모 | uspto-grants-2014_09 |