L-Glutamic Acid → Strontium glutamate
반응식
O.O.O.O.O.O.[NH2:7][C@H:8]([C:14]([O-:16])=[O:15])[CH2:9][CH2:10][C:11]([O-:13])=[O:12].[Sr+2:17].[OH-].[Sr+2].[OH-].N[C@H](C(O)=O)CCC(O)=O>>[NH2:7][C@H:8]([C:14]([O-:16])=[O:15])[CH2:9][CH2:10][C:11]([O-:13])=[O:12].[Sr+2:17]참가 물질
4
실험 절차
In a method according to the present invention strontium L-glutamate hexahydrate has been prepared by reacting strontium hydroxide with glutamic acid at a temperature in a range of from about 120° C. to about 135° C. and at a pressure of from about 1 to about 1.7 bar, optionally under an inert gas atmosphere, for a time period of from about 15 min to about 60 min to obtain strontium glutamate. The method may further involve a step of filtering the hot reaction mixture immediately after heating is stopped to remove precipitated calcium carbonate from the reaction mixture. Further details and guidelines for optimization of the reaction appears from Example 8.