(2-Methoxyethoxy)acetic acid → Methyl [4-({{4-[(4-butylphenyl)ethynyl]benzyl}[(2-methoxyethoxy)acetyl]amino}methyl)phenoxy]acetate
반응식
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[C:12][C:13]2[CH:33]=[CH:32][C:16]([CH2:17][NH:18][CH2:19][C:20]3[CH:31]=[CH:30][C:23]([O:24][CH2:25][C:26]([O:28][CH3:29])=[O:27])=[CH:22][CH:21]=3)=[CH:15][CH:14]=2)=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4].[CH3:34][O:35][CH2:36][CH2:37][O:38][CH2:39][C:40](O)=[O:41]>>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]([C:11]#[C:12][C:13]2[CH:14]=[CH:15][C:16]([CH2:17][N:18]([CH2:19][C:20]3[CH:21]=[CH:22][C:23]([O:24][CH2:25][C:26]([O:28][CH3:29])=[O:27])=[CH:30][CH:31]=3)[C:40](=[O:41])[CH2:39][O:38][CH2:37][CH2:36][O:35][CH3:34])=[CH:32][CH:33]=2)=[CH:9][CH:10]=1)[CH2:2][CH2:3][CH3:4]참가 물질
3
실험 절차
The titled compound was prepared following the procedure H using methyl {4-[({4-[(4-butylphenyl)ethynyl]benzyl}amino)methyl]phenoxy}acetate and (2-methoxyethoxy)acetic acid as a yellow oil (96%). HPLC, Rt: 5.17 min (Purity: 94.8%).
출처 및 근거
- ORD 기록
- ord-272d531cfc424664bba0a555a5e9bbb1
- 출처 데이터셋
- uspto-grants-2009_09