Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorodichloridic acid, phenyl ester → Ethyl 4-chloro-1-{[4-(methyloxy)phenyl]methyl}-1H-pyrrolo[3,2-c]pyridine-7-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorodichloridic acid, phenyl ester | HCID 13038 | — |
| 반응물 | Ethyl 1-{[4-(methyloxy)phenyl]methyl}-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carboxylate | HCID 57840819 | — |
| 생성물 | Ethyl 4-chloro-1-{[4-(methyloxy)phenyl]methyl}-1H-pyrrolo[3,2-c]pyridine-7-carboxylate | HCID 57840887 | — |
반응 단계
Prepared in a similar manner to Example 243(e) using ethyl 1-{[4-(methyloxy)phenyl]methyl}-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carboxylate (14.45 g) and phenyl dichlorophosphate (100 ml) to afford the title compound as a yellow oil (7.2 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07589206B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-e85f43810b5b43549820003a70ed2893 |
| 출처 메모 | uspto-grants-2009_09 |