Bis-(1H-imidazol-2-YL)-methanone → N-Methyl-3-({3-[2-(2,4,6-trifluorobenzyl)-7-(trifluoromethyl)-2H-indazol-3-YL]phenyl}ethynyl)benzamide

반응식

[F:1][C:2]1[CH:38]=[C:37]([F:39])[CH:36]=[C:35]([F:40])[C:3]=1[CH2:4][N:5]1[C:13]([C:14]2[CH:15]=[C:16]([C:20]#[C:21][C:22]3[CH:23]=[C:24]([CH:28]=[CH:29][CH:30]=3)[C:25]([OH:27])=O)[CH:17]=[CH:18][CH:19]=2)=[C:12]2[C:7]([C:8]([C:31]([F:34])([F:33])[F:32])=[CH:9][CH:10]=[CH:11]2)=[N:6]1.Cl.CN.C(C1NC=CN=1)([C:46]1[NH:47]C=CN=1)=O>CN(C=O)C>[CH3:46][NH:47][C:25](=[O:27])[C:24]1[CH:28]=[CH:29][CH:30]=[C:22]([C:21]#[C:20][C:16]2[CH:17]=[CH:18][CH:19]=[C:14]([C:13]3[N:5]([CH2:4][C:3]4[C:2]([F:1])=[CH:38][C:37]([F:39])=[CH:36][C:35]=4[F:40])[N:6]=[C:7]4[C:12]=3[CH:11]=[CH:10][CH:9]=[C:8]4[C:31]([F:32])([F:33])[F:34])[CH:15]=2)[CH:23]=1