HCID 57842589, 화합물 → HCID 57842918, 화합물
반응식
Br[C:2]1[CH:27]=[CH:26][C:5]([CH2:6][CH2:7][N:8]([CH3:25])[C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18]([CH2:21][CH3:22])(=[O:20])=[O:19])=[C:14]([C:23]#[N:24])[CH:13]=2)=[O:10])=[CH:4][CH:3]=1.[C:28]([C:31]1[CH:32]=[C:33]([NH:37][CH:38](C2C=CC(CCNC)=CC=2)[C:39]([OH:41])=[O:40])[CH:34]=[CH:35][CH:36]=1)(=[O:30])[NH2:29].[CH2:52]([O:59][C:60](NCC1C=C(N(C2C=CC=CC=2)C(=O)O)C=CC=1S(CC)(=O)=O)=[O:61])[C:53]1[CH:58]=[CH:57][CH:56]=[CH:55][CH:54]=1>>[CH2:52]([O:59][C:60]([NH:24][CH2:23][C:14]1[CH:13]=[C:12]([NH:11][C:9](=[O:10])[N:8]([CH2:7][CH2:6][C:5]2[CH:26]=[CH:27][C:2]([CH:38]([NH:37][C:33]3[CH:34]=[CH:35][CH:36]=[C:31]([C:28](=[O:30])[NH2:29])[CH:32]=3)[C:39]([OH:41])=[O:40])=[CH:3][CH:4]=2)[CH3:25])[CH:17]=[CH:16][C:15]=1[S:18]([CH2:21][CH3:22])(=[O:20])=[O:19])=[O:61])[C:53]1[CH:58]=[CH:57][CH:56]=[CH:55][CH:54]=1참가 물질
4
실험 절차
Using a procedure analogous to that used to synthesize 25B, 28F (227 mg, 0.69 mmol) was reacted with 28B to yield 28G (230 mg, 49%) as a yellow solid. MS (ESI) m/z 702.44 (M+H)+.
출처 및 근거
- ORD 기록