4-Formylbenzoic acid → 4-(3-Octyl-1,2,4-oxadiazol-5-yl)benzaldehyde

참여 물질

역할	이름	HCID	투입량
반응물	4-Formylbenzoic acid	HCID 12088	—
반응물	N'-hydroxynonanimidamide	HCID 5074022	—
생성물	4-(3-Octyl-1,2,4-oxadiazol-5-yl)benzaldehyde	HCID 86598532	34%

반응 단계

The same procedure as employed in the preparation of Example 277 (step a) but using 4-carboxybenzaldehyde and N-hydroxynonanimidamide gave the title compound as a beige solid (34%). 1H NMR (CDCl3, 300 MHz) δ 10.1 (s, 1H), 8.29 (d, 2H, J=8.3 Hz), 8.03 (d, 2H, J=8.3 Hz), 2.81 (t, 2H, J=7.4 Hz), 1.86-1.75 (m, 2H), 1.46-1.21 (m, 10H), 0.87 (m, 3H). HPLC (Condition A), Rt: 5.16 min (HPLC purity: 95.4%).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07592477B2
출처 데이터셋	uspto-grants-2009_09
ORD ID	ord-701c1f03980241c7ad958d767f09c87a
출처 메모	uspto-grants-2009_09