2-(2-Fluorophenyl)ethylamine → N-[2-(2-fluorophenyl)ethyl]-N-[4-(3-octyl-1,2,4-oxadiazol-5-yl)benzyl]amine

HRID 735953노트

반응식

HRID 735953 반응식
[CH2:1]([C:9]1[N:13]=[C:12]([C:14]2[CH:21]=[CH:20][C:17]([CH:18]=O)=[CH:16][CH:15]=2)[O:11][N:10]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[F:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH2:29][CH2:30][NH2:31]>>[F:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH2:29][CH2:30][NH:31][CH2:18][C:17]1[CH:20]=[CH:21][C:14]([C:12]2[O:11][N:10]=[C:9]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[N:13]=2)=[CH:15][CH:16]=1

참가 물질

3

반응물 2

HCID 6433572-(2-Fluorophenyl)ethylamineHCID 865985324-(3-Octyl-1,2,4-oxadiazol-5-yl)benzaldehyde

생성물 1

HCID 67187063N-[2-(2-fluorophenyl)ethyl]-N-[4-(3-octyl-1,2,4-oxadiazol-5-yl)benzyl]amine

실험 절차

The same procedure as employed in the preparation of Example 357 (step a) but using 4-(3-octyl-1,2,4-oxadiazol-5-yl)benzaldehyde and 2-(2-fluorophenyl)ethylamine gave the title compound as an oil.

후처리

  1. customThe same procedure as employed in the preparation of Example 357 (step a) but

출처 및 근거

ORD 기록
ord-e18fa8b43e284b708df937bed79a6bae
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07592477B2

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