Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-cyclopropyl-1H-imidazole → [5-(2-Cyclopropyl-imidazol-1-yl)-2-morpholin-4-yl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-cyclopropyl-1H-imidazole | HCID 17942383 | — |
| 반응물 | (5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 59793730 | — |
| 생성물 | [5-(2-Cyclopropyl-imidazol-1-yl)-2-morpholin-4-yl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 68841917 | 16% |
반응 단계
The title compound was prepared according to the procedure described for example 199 from (5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound CR) and 2-Cyclopropyl-1H-imidazole (CAS: 89532-38-7) (16% yield, white solid, MS (m/e): 526.3 (M+H, 100%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07595314B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-079f3da0462b4aa58a68ba1f2444ec9f |
| 출처 메모 | uspto-grants-2009_09 |