4-Fluorobenzaldehyde → 2-(Benzenesulfonyl)-3-(4-fluorophenyl)-1-phenylprop-2-en-1-one

반응식

[CH2:1]([S:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=[O:12])=[O:11])[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[O:3].[F:19][C:20]1[CH:27]=[CH:26][C:23]([CH:24]=O)=[CH:22][CH:21]=1>>[C:13]1([S:10]([C:1](=[CH:24][C:23]2[CH:26]=[CH:27][C:20]([F:19])=[CH:21][CH:22]=2)[C:2]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[O:3])(=[O:11])=[O:12])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

참가 물질

반응물 2

HCID 680234-Fluorobenzaldehyde

HCID 769491-Phenyl-2-(phenylsulphonyl)ethan-1-one

생성물 1

HCID 669379392-(Benzenesulfonyl)-3-(4-fluorophenyl)-1-phenylprop-2-en-1-one수율 62%

실험 절차

A solution of phenacylphenyl sulfone (0.01 mol) and 4-fluorobenzaldehyde (0.01 mol) was subjected to Method 1 of Procedure 4. The title compound, melting point 142-143° C., was obtained in 62% yield.

출처 및 근거

ORD 기록: ord-af43a685614b401eb53402e421fe455a
출처 데이터셋: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07595347B2

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