Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodoethane → HCID 86607915, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | Methyl cyclopent-1-ene-1-carboxylate | HCID 549129 | — |
| 반응물 | (+)-Benzylphenethylamine | HCID 1268086 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 생성물 | HCID 86607915 | HCID 86607915 | — |
반응 단계
According to the procedure of Example 53, Step 1, using (R)-N-benzyl-N-α-methylbenzylamine (4.2 mL, 4.24 g, 20 mmol), n-butyllithium (2.4 M, 7.4 mL), methyl 1-cyclopentene-1-carboxylate (1.3 mL, 1.29 g, 10.2 mmol), and iodoethane (1.6 mL, 3.12 g, 20 mmol), methyl (1S,2R)-2-amino-1-ethylcyclopentanecarboxylate was obtained as a mixture of two components (1.103 g) after purification on silica gel, eluting with 2% ethyl acetate/hexanes.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07595327B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-d7b5ccc4a5f24e288786848fc76d7ae0 |
| 출처 메모 | uspto-grants-2009_09 |