Acetonitrile → 1-(4-Bromo-benzyl)-3-phenyl-piperidine

참여 물질

반응 단계

5.632 g of 4-Bromobenzyl bromide and 2.422 g of 2-Phenylpiperidine (Array) in 50 mL of acetonitrile were stirred at room temperature and 6.229 g of potassium carbonate was added. The reaction was stirred at room temperature overnight. The solution was filtered through Celite and concentrated in vacuo to afford a brown solid. Purification was done by flash chromatography to afford product. Wt:0.908 g, 54% yield.

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