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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 737350생성일: 2026년 10월 26일

1-Chloro-4-(trifluoromethyl)benzene → 4-methyl-N-(4-(trifluoromethyl)phenyl)aniline

https://huagongshe.com/reaction/737350

반응식

참여 물질

역할이름HCID투입량
반응물1-Chloro-4-(trifluoromethyl)benzeneHCID 7394—
반응물p-ToluidineHCID 7813—
시약Ethyl 5-methylisoxazole-3-carboxylateHCID 76677—
시약2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineHCID 3393106—
촉매HCID 178439018HCID 178439018—
용매Dimethyl SulfoxideHCID 679—
생성물4-methyl-N-(4-(trifluoromethyl)phenyl)anilineHCID 1871279922.166%

반응 조건

온도60 °C

반응 단계

These solutions were added to a 384- well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose each of these solutions (200 nL each) into a 1536-well plate.

출처 및 근거

DOI10.1126/science.aar5169
출처 데이터셋Ahneman
ORD IDord-15078f42d6c545dbae57e7831a14f5dd
출처 메모Ahneman