Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Bromo-6-chloropyridine-3-carboxylic acid → 5-bromo-6-chloro-N-(4-((chlorodifluoromethyl)thio)phenyl)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| 반응물 | HCID 56624957 | HCID 56624957 | — |
| 생성물 | 5-bromo-6-chloro-N-(4-((chlorodifluoromethyl)thio)phenyl)nicotinamide | HCID 86702618 | — |
반응 단계
The title compound was prepared in an analogous fashion to that described in Stage 11.2 using 5-bromo-6-chloro-nicotinic acid and 4-((chloro-difluoromethyl)thio)aniline (Stage 18.3) to afford an off-white crystalline solid. HPLC (Condition 4) tR=6.78 min, UPLC-MS (Condition 3) tR=1.32 min, m/z=425 [M−H]−.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829195B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-2e20c9ebd32648309d5f92851d6f7241 |
| 출처 메모 | uspto-grants-2014_09 |