Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Methyl-2-thenoyl Chloride → 1-[[(3-Methyl-2-thienyl)carbonyl]amino]cyclohexanecarboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Methyl-2-thenoyl Chloride | HCID 2737605 | — |
| 반응물 | Methyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 22645079 | — |
| 생성물 | 1-[[(3-Methyl-2-thienyl)carbonyl]amino]cyclohexanecarboxylic acid methyl ester | HCID 32468521 | 47% |
반응 단계
581 mg (3 mmol) of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid phenylmethyl ester, and 482 mg (3 mmol) of 3-methyl-2-thiophenecarbonyl chloride was used instead of phenylacetyl chloride in the process according to Reference Example 1 to obtain 394 mg (47%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829209B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-115d9aa10ec54874a1d6b746c5951c72 |
| 출처 메모 | uspto-grants-2014_09 |