2-Bromobutane → 3-sec-Butyl-1H-indol-6-ylamine

HRID 73934

반응식

HRID 73934 반응식
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[CH:9][NH:10]2)=[CH:6][CH:5]=1)([O-])=O.Br[CH:14]([CH2:16][CH3:17])[CH3:15]>CC#N>[CH:14]([C:8]1[C:7]2[C:11](=[CH:12][C:4]([NH2:1])=[CH:5][CH:6]=2)[NH:10][CH:9]=1)([CH2:16][CH3:17])[CH3:15]

참가 물질

4

반응물 2

HCID 65542-BromobutaneHCID 785026-Nitro-1H-indole

생성물 1

HCID 574702003-sec-Butyl-1H-indol-6-ylamine

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

3-sec-Butyl-1H-indol-6-ylamine (B-14) was synthesized following the general scheme above starting from 6-nitroindole and 2-bromobutane. Overall yield (20%). HPLC ret. time 2.32 min, 10-99% CH3CN, 5 min run; ESI-MS 189.5 m/z (MH+).

후처리

  1. customOverall yield (20%)

출처 및 근거

ORD 기록
ord-9e49ae8cd83446ca958e78fb7ba17cdc
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08829204B2

연결된 노트

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