Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl iodoacetate → (6-Amino-1H-indol-3-yl)-acetic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl iodoacetate | HCID 12183 | — |
| 반응물 | 6-Nitro-1H-indole | HCID 78502 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | (6-Amino-1H-indol-3-yl)-acetic acid ethyl ester | HCID 66675483 | — |
반응 단계
(6-Amino-1H-indol-3-yl)-acetic acid ethyl ester (B-17) was synthesized following the general scheme above starting from 6-nitroindole and iodo-acetic acid ethyl ester. Overall yield (24%). HPLC ret. time 0.95 min, 10-99% CH3CN, 5 min run; ESI-MS 219.2 m/z (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829204B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-ed116ac2db13497eaec502a4321fada4 |
| 출처 메모 | uspto-grants-2014_09 |