Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Tert-Butylphenol → 4-Bromo-2-tert-butylphenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Tert-Butylphenol | HCID 6923 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 4-Bromo-2-tert-butylphenol | HCID 97068 | 99.3% |
반응 단계
To a solution of 2-tert-butylphenol (250 g, 1.67 mol) in CH3CN (1500 mL) was added NBS (300 g, 1.67 mol) at room temperature. After addition, the mixture was stirred at room temperature overnight and then the solvent was removed. Petroleum ether (1000 mL) was added, and the resulting white precipitate was filtered off. The filtrate was concentrated under reduced pressure to give the crude 2-tert-butyl-4-bromophenol (380 g), which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829204B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-97ca45fe2d5043acb3e89dba7009a4e9 |
| 출처 메모 | uspto-grants-2014_09 |