Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-(4-Chloro-2-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 3-Chloro-6-isothiocyanatotoluene | HCID 90021 | — |
| 반응물 | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-(4-Chloro-2-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one | HCID 18968210 | 58.9% |
반응 단계
The title compound was prepared by the procedure described in Example 1 using 9.18 g of 4-chloro-2-methylphenyl-isothiocyanate, 7.68 g of sarcosine ethyl ester hydrochloride, 12.0 g of triethyl amine, and 300 mL of chloroform. Crystallization from diethyl ether afforded the title compound (7.5 g) as an off-white solid, m.p. 113°-115° C. Anal. Calcd. for C11H11Cl N2O S: C, 51.87; H, 4.35; N,11.00. Found: C, 51.72; H, 4.17; N, 10.88. Mass spectrum (El, M.+) m/z 254/256.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05554607 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-eef7ef530d104d5283788085c867fb32 |
| 출처 메모 | uspto-grants-1996_09 |